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The primary objective of WP2 is to support the development of the material technologies from WP1 through targeted implementation and optimisation of advanced manufacturing techniques, which will facilitate their progression from a material production state to a component or end-application production state. This WP forms a crucial step in the development chain as these techniques will enable fabrication of complex prototype orthopaedic and vascular implant designs WP4.

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This WP will apply the materials, processes and test data generated in WPs 1 — 3 to develop vascular and orthopaedic implants with improved mechanical performance and controllable degradation rates based on the technologies developed. Five orthopaedic implants, specifically trauma plates and bone scaffolds for critical defects will be developed to enable high load-capacity fixation.

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Research Programme The scientific objective of the BioImplant ITN is to develop and implement improved bioabsorbable materials for vascular and orthopaedic implant applications. The specific research objectives of the BioImplant ITN are as follows: Enhance the mechanical properties of polymer-based bioabsorbables through novel processing technologies. Seamus Higson. Richard Bibb.

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Control of gelation, degradation and physical properties of polyethylene glycol hydrogels through the chemical and physical identity of the crosslinker. Journal of Materials Chemistry B , 5 14 , Self-healing pH-sensitive cytosine- and guanosine-modified hyaluronic acid hydrogels via hydrogen bonding. Polymer , , Duarte, Rui L. Chemie Ingenieur Technik , 88 11 , Dynamic three-dimensional micropatterned cell co-cultures within photocurable and chemically degradable hydrogels.

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